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Permeability of acetylcellulose ultrafiltration membranes with regard to biologically active substances

Rozhanskaia, T.I.; Margolina, N.A.; Podsukhina, G.M.; Selezneva, A.A.; Dubiaga, V.P.

Prikladnaia Biokhimiia i Mikrobiologiia 12(2): 287-290

1976

ISSN/ISBN: 0555-1099
PMID: 1005367
Document Number: 101740
The permeability of standard Soviet ultrafiltration membranes prepared from cellulose acetates was investigated with respect to biologically active substances (hemoglobin, trypsin, ribonuclease, vitamin B12, hydroxytetracycline) and inorganic salt (KH2PO4). The arrest of a substance by a membrane of a certain structure depended primarily on the size of the substance macromolecule in the solution. The filtration rate was related to the membrane type, pressure gradient and composition of the filtered solution. Potential use of the tested membranes is described.

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