Structural changes in ganglioside micelles during interaction with serotonin
Chupriianova, N.E.; Iampol'skaia, G.P.; Veĭnberg, A.I.; Samokhvalov, G.I.
Biofizika 21(3): 453-458
1976
ISSN/ISBN: 0006-3029 PMID: 963094 Document Number: 100711
Structure changes of ganglioside micelles in the process of serotonin bonding are considered. It was shown by viscosimetric and differential refraction studies that stretching of elliptical ganglioside micelles in the serotonin bonding process took place. The scope of micelles form changes depends on the pH value. An increase of the micelles summary negative charge at pH 9 increased the number of bonding centres and simultaneously caused deeper deformation of micelles due to the repulsion of the identically charged groups.