Partial purification of nucleopeptides from rabbit skeletal muscle by the tannin-caffeine procedure
Lomako, W.; Mejbaum-Katzenellenbogen, W.
Archivum Immunologiae et Therapiae Experimentalis 24(5): 785-792
1976
ISSN/ISBN: 0004-069X PMID: 999480 Document Number: 100416
After precipitation of acid-soluble proteins from sulfosalicylic acid extracts of rabbit skeletal muscles with tannin at neutral pH, the remaining material still formed insoluble complexes with tannin. After removing tannin with caffeine complexes subjected to column chromatography on Dowex 1 x 8 gave four fractions containing both amino acids and nucleotides. It was concluded that the isolated material contains nucleopeptides, besides nucleotides.