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The effects of EGF, TGF-beta and insulin on the growth of rabbit's skeletal muscle satellite cell

Xu, P.; Gu, X.

Zhonghua Kou Qiang Yi Xue Za Zhi 35(4): 289-291

2000

ISSN/ISBN: 1002-0098
PMID: 11780513
Document Number: 522375
To investigate the effects of epithelium growth factor (EGF), transforming growth factor-beta(TGF-beta) and insulin on the growth of cultured rabbit's skeletal muscle satellite cells. After treatment with EGF, TGF-beta and insulin, MTT method was used to study the proliferation of the cells. EGF and insulin could promote the growth of the satellite cells more significantly than that of TGF-beta. It implied that there was a close relationship between the effects of three agents and the regeneration of injured muscles. This kind of positive effect appeared in a dose- and time-dependent manner.

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