Release of highly soluble substances from inert matrices in cases of two-sided attack of the solvent
Mihailova, D.; Slavchev, P.
Arzneimittel-Forschung 26(7): 1279-1280
1976
ISSN/ISBN: 0004-4172 PMID: 1036913 Document Number: 100309
The present work is an extension of some of our earlier investigations on the release of soluble substances in inert matrices. There have been described the cases of two-sided attack on the inert matrices (PVC and PE) by the solvent. The theoretical considerations of the cases for the two-sided attack were experimentally confirmed. The values of the diffusion coefficients, which correspond to the calculated ones in the cases of one-sided attack, were calculated as well.