Aminoacylation of rat liver tRNA under different experimental conditions
Vynodradova, R.P.; Kicherenko, M.E.; Efymets, T.I.
Ukrains'kyi Biokhimichnyi Zhurnal 48(1): 58-60
1976
ISSN/ISBN: 0041-610X PMID: 1258162 Document Number: 100099
The studies were performed in methionine, lysine and glycine aminoacylation of the total tRNA preparations isolated from the rat liver 3 h after total irradiation with X-rays with a dose of 800 R as well as after administration of nicotinic acid and proserine 4 h before decapitation of the animals. The tRNA preparations isolated from the irradiated animals liver are established to accept methionine, glycine and lysine to a less extent as compared with the normal state. The tRNA preparations isolated from the animal liver after administration of nicotinic acid accept methionine and glycine to a less degree and in the tRNA preparations from the liver of animals which were administered proserine the acceptance intensity lowers only with respect to lysine.