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18-hydroxylated steroids in human hypertension - clinical study

Genard, P.; Palem-Vliers, M.; van Cauwenberge, H.; Eechaute, W.

Endocrinologia Experimentalis 10(1): 53-58

1976

ISSN/ISBN: 0013-7200
PMID: 1083801
Document Number: 99792
The detection of two unknown urinary steroids called x and y in various patients was previously reported. Compound x was tentatively characterized as a derivative of dihydro-18-hydroxy-DOC with two additional polar groups. In this communication clinical observations of a set of 25 hypertensive patients are presented. Compound x alone was found in 4 cases, compound y alone 4 cases and both compound x and y in 5 cases. In several other cases, hypokalemia and/or a decreased urinary Na+/K+ ratio were found.

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Du, Z.M.; Huang, H.H.; Chen, X.Y.; Zhong, D.F. 2000: Study on hydroxylated metabolites of benproperine in human urine Yao Xue Xue Bao 35(12): 916-920
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Garcia, C.R.; Pincus, G.; Rock, J. 1958: Effects of three 19-nor steroids on human ovulation and menstruation American Journal of Obstetrics and Gynecology 75(1): 82-97
Leon, M.-M.; Mitu, F. 2013: The clinical-epidemological study of drugs used to treat arterial hypertension and associated comorbidities Revista Medico-Chirurgicala a Societatii de Medici Si Naturalisti Din Iasi 117(2): 488-494
Sirakova, V.; Penkov, N.; Kaponov, K. 1986: Clinical study of the beta-blocker chlorpropanol (tobanum) in hypertension patients Vutreshni Bolesti 25(1): 35-41