The failures of the exclusive physiotherapy of carcinoma of the uterine cervix. Study of their topography and their causes
Dubois, J.B.; Pourquier, H.
Journal de Radiologie d'Electrologie et de Medecine Nucleaire 57(5): 421-427
1976
ISSN/ISBN: 0368-3966 PMID: 825642 Document Number: 99793
In a series consisting of 400 cases of carcinoma of the uterine cervix, the authors encountered a therapeutic failure rate of 43,5%-5,8% were due to advanced localized disease, 29,4% to locoregional recurrence, and 8,3% to tardive isolated metastases. Of the 126 recurrences, 25 were localized to the cervix or vagina, 67 were elsewhere within the pelvis, and 34 were both localized and pelvic. These recurrences, more frequently found in the advanced stages of cervical neoplasia, are usually due to insufficient external or internal irradiation of the parametria or central part of the pelvis. The current methods of external irradiation using high energy sources in combination with curietherapy using a more appropriately suited material tend to decrease the failure rate due to insufficient irradiation.