Fixed drug eruption induced by indapamide. Cross-reactivity with sulfonamides
De Barrio, M.; Tornero, P.; Zubeldia, J.M.; Sierra, Z.; Matheu, V.; Herrero, T.
Journal of Investigational Allergology and Clinical Immunology 8(4): 253-255
1998
ISSN/ISBN: 1018-9068 PMID: 9777542 Document Number: 990
Indapamide is a nontiazidic sulfonamide diuretic which has not been previously reported as a cause of fixed drug eruption. We describe a patient who experienced several episodes of fixed drug eruption during treatment with indapamide. The diagnosis was confirmed by positive controlled oral challenge test. The possible existence of cross-reactivity with other sulfonamide derivatives was investigated by controlled oral challenge test with sulfamethoxazole, sulfadiazine and furosemide, with the tests with sulfamethoxazole and sulfadiazine resulting positive.
Document emailed within 1 workday
