Lethal infection with BCG in thymectomized mice

Moroz, A.M.; Galkin, I.M.; Litvinov, V.I.; Il'ina, I.N.; Averbakh, M.M.

Biulleten' Eksperimental'noi Biologii i Meditsiny 82(12): 1464-1465

1976


ISSN/ISBN: 0365-9615
PMID: 1023978
Document Number: 98830
Investigations carried out on CBA mice demonstrated that adult mice to which mycobacteria BCG were injected intravenously 12 months after thymectomy (in a dose of 2 mg for a period of 2 1/2 months) died of disseminated BCG infection against the background of depression of hypersensitivity of delayed type. The usual vaccine process developed in the sham-operated animals.

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