Enhanced development of metastatic foci in thymectomized, irradiated, and bone marrow-reconstituted mice
Makidono, R.; Nomoto, K.; Takeya, K.
Gan 67(5): 645-649
1976
ISSN/ISBN: 0016-450X PMID: 190077 Document Number: 97399
Development of metastatic foci in the lung, liver and lymph nodes was enhanced by thymectomy, irradiation and bone marrow reconstitution in C3H/He mice inoculated i.m. with MH-134 hepatoma cells. Enhanced development may be ascribed to enhanced growth of tumor cells after lodging at such organs.
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