Human placental alcohol dehydrogenase
Krasner, J.; Tischler, F.; Yaffe, S.J.
Journal of Medicine 7(3-4): 323-332
1976
ISSN/ISBN: 0025-7850 PMID: 13137 Document Number: 97111
Alcohol dehydrogenase derived from the term human placenta was investigated in the 104,000 .times. g supernatant fraction. Kinetic experiments yielded an average Vmax of 6.1 units, a Km of 5 .times. 10-3 M and optimum activity at pH 10.0. Electrophoresis at pH 9.6 in glycine buffer showed 4 bands; only 2 bands were observed at pH 8.6. Properties of this placental enzyme may be unique and its participation in the overall metabolic function of this tissue is unclear.
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