Effect of Ukrain on human liver alcohol dehydrogenase activity in vitro
Jagiełło-Wójtowicz, E.; Dudka, J.; Dawidek-Pietryka, K.
Drugs under Experimental and Clinical Research 26(5-6): 337-339
2000
ISSN/ISBN: 0378-6501 PMID: 11345049 Document Number: 515926
In the present study it was found that Ukrain inhibits the ethanol oxidation process catalyzed by human alcohol dehydrogenase (ADH). Ukrain at a concentration of 10(-6), 2.5 x 10(-6), and 5.0 x 10(-6) M decreased liver ADH activity in the presence ethanol (approximately 8.41%, 13.28%, 16.69%, respectively) as well as in the presence of methanol (approximately 13.29%, 19.07% and 42.20%, respectively).
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