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Plasma drug concentrations in therapeutics

Hooper, W.D.; Tyrer, J.H.; Eadie, M.J.

Medical Journal of Australia 1(10): 313-319

1976

ISSN/ISBN: 0025-729X
PMID: 1272103
Document Number: 96960
The literature describing drugs assay in plasma and its value for optimal therapy for individual patients is expanding rapidly. The present review seeks to clarify the rationale underlying the assay of plasma concentrations of drugs, and it attempts to define principles for judging the likely value of assaying a particular drug. Examples are given of drugs which are being usefully measured in clinical practice. The most commonly used assay techniques are briefly described, and their principal advantages and limitations are indicated.

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