The significance of histological findings for the final clinical evaluation in acute viral hepatitis
Metzner, C.; Kirsch, W.D.; Haupt, R.; Arnoldt, K.H.
Zeitschrift für die Gesamte Innere Medizin und ihre Grenzgebiete 30(14): 467-471
1975
ISSN/ISBN: 0044-2542 PMID: 1210458 Document Number: 96025
Clinical and morphological findings of 406 patients who fell ill from a virus hepatitis were established according to the data and statistically evaluated to find relations between clinical, serochemical and histological criteria. The results were tested statistically. Clinical and paraclinical findings at the end of the hospital treatment give no evidence concerning the histological degree of cure of the acute virus hepatitis. In normalised clinical and serochemical findings we could morphologically prove an acute hepatitis still in 27.4%. Anamnestic data and severity of the clinical course have no relation to the histological diagnosis at the end of the hospital treatment with clinical and serochemical recovery. Therefore, at the end of the hospital treatment we recommend the liver biopsy as final examination. The most favourable date of the liver biopsy would, however, be between the 6th and 12th week after discharge.