Minimal daily requirement of folic acid in normal Indian subjects
Banerjee, D.K.; Maitra, A.; Basu, A.K.; Chatterjea, J.B.
Indian Journal of Medical Research 63(1): 45-53
1975
ISSN/ISBN: 0019-5340 PMID: 1213710 Document Number: 95245
Six normal Indian subjects (5 males, 1 female) were given a diet low in folic acid, 15 mu g/day. Folacin deficiency developed after 6 weeks as evidenced by subnormal serum folacin and declining erythrocyte folacin levels. The diet was then supplemented with graded doses from 25 to 100 mu g folic acid/day. The dose at which both serum and erythrocyte folacin regained normality was considered to be the minimum daily folic acid requirement; in the normal Indian subjects this was 75 mu g/day.