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Peripheral arterial and venous concentrations of various androgens in patients with and without hirsutism

Chang, R.J.; Abraham, G.E.

Obstetrics and Gynecology 46(5): 549-550

1975

ISSN/ISBN: 0029-7844
PMID: 127957
Document Number: 94182
The mean peripheral arteriovenous difference for dehydroepiandrosterone (DHEA), dehydroepiandrosterone sulfate (DHEA-S), androstenedione (A), testosterone (T), 5ALPHA-dihydrotestosterone (DHT), and 17-hydroxyprogesterone (17-P) has been calculated in 7 nonhirsute and 9 hirsute women. No significant difference was found between peripheral artery and vein concentrations for all steroids measured in both groups of women studied. Since steroid concentrations in peripheral arterial samples are not expected to differ from those from ovarian and adrenal arteries, it is concluded that peripheral venous steroid levels adequately represent the steroid concentrations of arterial blood delivered to steroid-producing tissue.

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