Effect of HL-A system antigen differences on the specificity of produced anti-leukocyte antibodies
Maczyńska-Rusiniak, B.; Zupańska, B.
Acta Haematologica Polonica 6(4): 261-266
1975
ISSN/ISBN: 0001-5814 PMID: 1199674 Document Number: 93463
In Rh-negative volunteers immunized for development of anti-D antibodies the specificity of developed anti-leucocyte antibodies was determined. The specificity of these antibodies was analysed in relation to HL-A antigenic differences determined in donors and recipients. The antigenic power of sublocus II was found to be superior to that of sublocus I. Another observation was more frequent production of cross-reacting antibodies. A trial of analysis of these volunteers in whom no antileucocyte antibodies developed during immunization with blood was undertaken.