Ornithine decarboxylase activity in regenerating liver from rats adapted to controlled feeding schedules
Barbiroli, B.; Moruzzi, M.S.; Tadolini, B.; Monti, M.G.
Journal of Nutrition 105(4): 408-412
1975
ISSN/ISBN: 0022-3166 PMID: 1167586 Document Number: 92452
Ornithine decarboxylase activity was studied during the early stages of liver regeneration after partial hepatectomy in rats adapted to having food available for 8 h daily. Liver ornithine decarboxylase showed obvious daily fluctuations during liver regeneration. The time of day of surgery affected the pattern of enzyme activity after partial hepatectomy. A first postoperative peak of activity was constantly found 6 h after surgery. Another peak of activity was near the end of the dark period independent of the timing of the operation. Food intake induced a further peak of activity in the feeding period. Due to the interaction between controlled feeding schedules and partial hepatectomy, the timing of the operation was essential to obtaining a better resolution of the different peaks of activity in those conditions.