Ionic calcium and magnesium from pharmaceutical product BEROCCA effects on neuromuscular excitability
Stratone, A.; Stratone, C.; Chiruţă, R.; Zaharia, D.; Căruntu, L.; Diaconu, M.; Stefancu, O.; Topoliceanu, F.
Revista Medico-Chirurgicala a Societatii de Medici Si Naturalisti Din Iasi 109(1): 200-205
2005
ISSN/ISBN: 0048-7848 PMID: 16607855 Document Number: 9227
The important physiological role of calcium and magnesium ions is all over recognised, about a lot of enzymatic reactions. Magnesium deficit produce neuromuscular hyper-reactivity, psychic reactions, functional hypoparathyroidism, increase of K+ channels membranes permeability, while hypermagnesemia decrease Ach release from neuromuscular synapsis, with post-synaptic excitability decreasing. Using BEROCCA (Hoffman la Roche) 1 cp/day, 30 days at the teenagers with behaviour troubles and at a goup of pregnant women (trimester I-III) with paresthesia, irritability, sleeplessness, we observed an improve of clinical signs, increasing plasma Ca2+ and Mg2+. EEG and EMG prove the beneficial effects of pharmaceutical product BEROCCA.
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