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DNA and antibodies to DNA in Aleutian mink disease

Slugin, V.S.; Prozorovskaia, N.N.; Belokrinitskiĭ, D.V.

Biulleten' Eksperimental'noi Biologii i Meditsiny 80(8): 84-87

1975

ISSN/ISBN: 0365-9615
PMID: 1182310
Document Number: 91974
Free DNA and various types of antibodies to DNA were determined in the blood serum and plasma of minks which contracted Aleutian disease (AD) spontaneously and of minks experimentally infected with this disease. Healthy minks and other animals served as controls. It was found that a higher incidence of antibodies to DNA of the 2nd and 3rd types in high titres (1: 80-1: 2560) was characteristic of the experimental group of animals. Besides, a free polymeric DNA was more frequently revealed in the experimental group of animals.

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