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Optimization of the nutrient medium for the biosynthesis of phytotoxic metabolites of Myrothecium verrucaria VKMF-183

Elisashvili, T.A.; Borovkov, A.V.

Prikladnaia Biokhimiia i Mikrobiologiia 11(6): 877-879

1975

ISSN/ISBN: 0555-1099
PMID: 1239763
Document Number: 91377
By means of mathematical planning of the experiment optimal concentrations of components of the nutrient medium were found for the biosynthesis of phytotoxic metabolites by the soil fungus Myrothecium verrucaria VKMF-183. The composition of the optimized medium were: glucose--8%, KH2PO4--0.05%, asparagine--0.35%, ammonium tartrate--0.07%, MgSO4--0.03%, solution of trace elements--0.1%. The accumulation of phytotoxic metabolites in the above medium was 2.4 times higher than in the initial medium.

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