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Variability of influenza A2 viruses in nature

Sokolov, M.I.; Podcherniaeva, R.I.

Voprosy Virusologii 4: 424-429

1975

ISSN/ISBN: 0507-4088
PMID: 1216834
Document Number: 91006
A comparative study of variability of the properties of influenza A2 viruses isolated in different epidemic years (1964-1965, 1968-1969, 1972-1973) showed that in the course of influenza virus evolution changes occurred not only in the antigenic properties of surface proteins (hemagglutinins and neuraminidase) but in a number of other properties as well. In contrast to previously circulating strains, influenza A2 virus strains isolated in the epidemic of 1971-1972 were found to have higher reproducing and neuraminidase activities, greatly increased thermostability and the capacity to induce viremia regularly in white mice.

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