Some patterns of RNA synthesis in the proliferation induction process in a stationary culture of Chinese hamster cells
Zosimovskaia, A.I.; Terslolj, V.V.
Tsitologiia 17(3): 266-271
1975
ISSN/ISBN: 0041-3771 PMID: 1135947 Document Number: 90938
An increase in the incorporation of eH-uridine into RNA and in the cell membrane permeability for 3H-uridine in stationary culture cells after medium replenishment were found to be parallel. Increase in the RNA synthesis occurs practically in all cells stimulated to proliferate and is not accompanied by swelling nucleii, as demonstrated by measuring the projected areas of nucle on fixed cells. The rise in RNA synthesis as a response to proliferative stimulus is pronounced at every cell density but with increasing cell density fall in the magnitude of the response occurs.