Top Abstract Purchase Related
Home
>
Node
>
Subnode

Electrophysiological evidence for an inhibitory action of diazepam upon cat brain cortex

Zakusov, V.V.; Ostrovskaya, R.U.; Markovitch, V.V.; Molodavkin, G.M.; Bulayev, V.M.

Archives Internationales de Pharmacodynamie et de Therapie 214(2): 188-205

1975

ISSN/ISBN: 0003-9780
PMID: 1156029
Document Number: 89848
Diazepam was shown to increase postexcitatory inhibition within the brain cortex as revealed by its influence upon the recovery cycles both of intracortical and primary responses. The specific interrelationship between diazepam and some drugs affecting brain GABA level suggests the possibility of a GABA mediated mechanism in the diazepam effect. The sensitivity of the brain cortex to diazepam is not lower than that of the amygdala and significantly higher than that of the hippocampus.

Document emailed within 1 workday
Secure & encrypted payments

Dun, N.J.; Karczmar, A.G. 1981: Evidence for a presynaptic inhibitory action of 5-hydroxytryptamine in a mammalian sympathetic ganglion Journal of Pharmacology and Experimental Therapeutics 217(3): 714-718
Garbossa, G.; Gutnisky, A.; Nesse, A. 1994: The inhibitory action of aluminum on mouse bone marrow cell growth: evidence for an erythropoietin- and transferrin-mediated mechanism Mineral and Electrolyte Metabolism 20(3): 141-146
Mohanakumar, K.P.; Sood, P.P. 1985: Inhibitory action of morphine on adenosine triphosphatase content in the whole and individual nuclei of mouse brain during the tolerance-dependence development and its reversal by naloxone Journal für Hirnforschung 26(6): 695-708
Petrek, J.; Lisonĕk, P. 1987: Electrophysiological expression of quick activation of cat's cortex by acoustic stimuli Acta Universitatis Palackianae Olomucensis Facultatis Medicae 116: 81-96
Jiang, Y.; Zhong, G.G.; Qi, H.; Ma, X.Y. 1993: Antioxidative action of soyasaponin monomers I, A1, A2, and their inhibitory effects on action potential and beating of myocardiocytes in culture Zhongguo Yao Li Xue Bao 14(3): 269-273
Palmer, M.R.; Hoffer, B.J. 1980: Catecholamine modulation of enkephalin-induced electrophysiological responses in cerebral cortex Journal of Pharmacology and Experimental Therapeutics 213(2): 205-215
Mariño, J.; Schummers, J.; Sur, M. 2003: Combination of new electrophysiological and imaging techniques in the study of primary visual cortex function Revista de Neurologia 36(10): 944-950
Niedermeyer, E. 1970: Intravenous diazepam and its anticonvulsive action Johns Hopkins Medical Journal 127(2): 79-96
Golubev, N.P.; Bogdarin, I.A.; Manannikov, A.S.; Mediantsev, V.E. 1987: Pathophysiological characteristics of a number of electrophysiological and biochemical indices of the cerebral cortex neurons in cats exposed to strychnine Patologicheskaia Fiziologiia i Eksperimental'naia Terapiia 6: 30-32
Veseliunene, M.A.; Gutman, A.M.; Lesene, V.A. 1971: Effect of nembutal upon the inhibitory wave of antidromically evoked potential in the motor cortex of the cat Farmakologiia i Toksikologiia 34(5): 520-522
Zakusov, V.V.; Profir'eva, R.P. 1975: Intracellular mechanism of the action of imipramine and diazepam Biulleten' Eksperimental'noi Biologii i Meditsiny 80(10): 67-69
Benke, A.; Balogh, A.; Reich-Hilscher, B. 1979: The solubilizer of diazepam (valium)--its action on respiration Der Anaesthesist 28(1): 24-28
Panto, M.R.; Cicirata, F.; Angaut, P.; Parenti, R.; Serapide, F. 1995: The projection from the primary motor and somatic sensory cortex to the basilar pontine nuclei. a detailed electrophysiological and anatomical study in the rat Journal für Hirnforschung 36(1): 7-19
Parfitt, K.D.; Gratton, A.; Bickford-Wimer, P.C. 1990: Electrophysiological effects of selective D1 and D2 dopamine receptor agonists in the medial prefrontal cortex of young and aged Fischer 344 rats Journal of Pharmacology and Experimental Therapeutics 254(2): 539-545
Shannon, H.E.; Herling, S. 1983: Discriminative stimulus effects of diazepam in rats: evidence for a maximal effect Journal of Pharmacology and Experimental Therapeutics 227(1): 160-166
Serdiuk, S.E.; Gmiro, V.E. 2012: Adrenaline potentiates antiepileptic but not sedative action of diazepam in rats Rossiiskii Fiziologicheskii Zhurnal Imeni I.M. Sechenova 98(2): 236-241
Kozák, I.; Sourek, K.; Zvĕrina, E.; Trávnícek, V. 1970: Monitoring the diazepam (Valium) level in the brain during hypothermia Ceskoslovenska Neurologie 33(4): 184-187
Takashina, J. 1956: Studies on action mechanisms of antituberculous drugs. I. Studies on inhibitory action of SM, PAS, INH against BCG dehydrogenase Science Reports of the Research Institutes, Tohoku University, Series C: Medicine 7(2): 187-194
Follmer, C.H.; Lum, B.K. 1982: Protective action of diazepam and of sympathomimetic amines against amitryptyline-induced toxicity Journal of Pharmacology and Experimental Therapeutics 222(2): 424-429
Otero, J.; Sierra, G.; Acuña, C.; Domínguez, R. 1970: Effect of diazepam on electrocardiography changes induced by stimulating various brain structures Revista Clinica Espanola 117(4): 407-414