Role of cations and surface membrane proteins in the adhesion of rat liver parenchymal cells. I. Effect of dirrerent perfusion periods on the structure of cellular junctions
Komissarchik, I.I.; Snigirevskaia, E.S.; Vinnichenko, L.N.; Ivanovskaia, E.G.
Tsitologiia 17(1): 35-41
1975
ISSN/ISBN: 0041-3771 PMID: 1118899 Document Number: 89267
Electronmicroscopic study of the structure of the rat liver cell junctions in the normal conditions and after 90 min. perfusion by the physiological solution showed 4 kinds of specialized junctions between the hepatocytes with typical structure: tight junction, gap junction, intermediate junction, and desmosomes. The long perfusion does not cause visible changes in the contact structure or the sizes of the intercellular space. The preservation of the tight junction after the long perfusion is demonstrated by the lanthanum tracer: lanthanum is never found in the tight junction and in the bile capillary. Lanthanum reveales globular structure of the middle layer of the gap junction.