Analysis of certain nodal features of regenerative reactions
Gusak, P.P.
Arkhiv Anatomii Gistologii i Embriologii 68(6): 102-115
1975
ISSN/ISBN: 0004-1947 PMID: 1098622 Document Number: 88617
The increased degree of death of cells due to increased functional stresses may serve as a starting factor responsible for the compensatory growth. This fact allows considering reparative regeneration and compensatory growth as phenomena of the same class. Different forms of reparative growth (intracellular regeneration and proliferation of cells, endomorphosis and epimorphosis) serve to concrete tasks of reparation at different levels of organization of the morphological substrate. They are sustained by endogeneous morphogenetical mechanisms developing independently of other levels and of environment. In the subsystem of lover levels of organization the involved morphogenetical mechanisms may sustain not only compensation of the lost structures but also their overproduction. As a rule the program of reparative processes may be realized on higher (e. g. organic) level but partly. Among available criteria of regeneration at the present time the calculation of mitoses should be considered the most adequate one. The systemic approach may prove to be a perspective method both for estimation of regeneratory effect and for deeper analysis of reparative phenomena in general.