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Features of changes in bioelectric reactions of the cerebral cortex in rats with deafferentation pain syndrome

Kryzhanovskiĭ, G.N.; Reshetniak, V.K.; Kukushkin, M.L.; Smirnova, V.S.

Biulleten' Eksperimental'noi Biologii i Meditsiny 113(3): 234-236

1992

ISSN/ISBN: 0365-9615
PMID: 1421212
Document Number: 395466
In rats with pain syndrome after sciatic nerve section the authors studied spontaneous and evoked bioelectric activity in sensomotor cerebral cortex of both hemispheres. Electrocorticogram showed the presence of hyper-synchronic discharges and paroxysmal peak-wave (700-800 mV) activity in contralateral hemisphere. While stimulating the injured limb the threshold of evoked potentials (EP) was observed to decrease, its amplitude to increase and focus maximum EP activity to extend.

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