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Immunoelectrophoretic analysis of reactions between heparin and pregnancy proteins

Zorin, N.A.; Zorina, R.M.

Voprosy Meditsinskoi Khimii 30(4): 26-28

1984

ISSN/ISBN: 0042-8809
PMID: 6209851
Document Number: 232969
A procedure is described for the study of reactions between heparin and human blood serum proteins using zonal electrophoresis in agar gel containing various amounts of heparin. The alterations occurring were registered by means of cross immunoelectrophoresis. A shape of the pregnancy protein precipitates and their electrophoretic mobility were altered depending on concentration of the glycosaminogly can present. Characteristic properties of the reactions between heparin and pregnancy proteins are discussed as well as the perspectives of the use of this method for study of proteins reacting with heparin.

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