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Polymyxin M biosynthesis by Bacillus polymyxa Ross depending on the source of ammonium nitrogen and its concentration in the medium

Pavliuk, I.V.; Bogats'kii, M.O.; Preobrazhens'kii, L.M.; Evseeva trm

Mikrobiolohichnyi Zhurnal 37(5): 590-593

1975

ISSN/ISBN: 0201-8462
PMID: 176560
Document Number: 88526
The effect of ammonium salts on polymyxin M biosynthesis by the producer B. polymyxa Ross on a medium containing flour as a source of carbohydrate nutrition was studied. Culture growth, antibiotic accumulation and consumption of main nutrients were studied depending on a change in the ammonium sulfate content in the medium. The greatest productivity of the medium may be reached using ammonium sulfate in a concentration up to 2% for N nutrition.

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