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Incorporation of exogenous DNA and its localization in the chromosomes of the host cell

Mińarrová, E.; Keprtová, J.; Nebola, M.; Spurná, V.

Neoplasma 22(5): 491-494

1975

ISSN/ISBN: 0028-2685
PMID: 1196432
Document Number: 88013
Incorporation of isologous 3H-DNA of exogenous origin into chromosomes of the L cells was investigated by means of autoradiographical technique. It was shown that during short time intervals of incubation of 3H-DNA with the host cells (1--3 hr), nearly double quantity of the mitoses was labelled, when compared with 3H-TdR used as a control. During longer time intervals, no difference between number of the mitoses labelled with 3H-TdR and exogenous isologous 3H-DNA was observed.

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