Castleman's disease: a clinicopathologic study of 12 cases
Kasantikul, V.; Panyavoravut, V.; Benjavongkulchai, S.; Panichabhongse, V.
Journal of the Medical Association of Thailand 80(3): 195-201
1997
ISSN/ISBN: 0125-2208 PMID: 9175388 Document Number: 864
Castleman's disease observed in 12 Thai patients was investigated. The male to female ratio was 1 : 3. Peak prevalence was in the third and fourth decades. It is suggested that the disease in Orientals tends to have extrathoracic mass more often than in Caucasians. Solitary non-tender slow growing mass was the most common symptom. Generalized lymphadenopathy in association with cutaneous plasmocytoma was noted in one example while asymptomatic pelvic lesion in a patient was discovered incidentally. Histologically, the hyaline-vascular type was found in 8 instances, the remainders were plasma-cell type. Surgery was effective for localized lesions while systemic form could benefit from chemotherapy.
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