Is it worth preserving the nerves in a transplanted kidney?
Gombos, A.; Stopek, D.; Jacina, J.
Folia Morphologica 23(4): 320-322
1975
ISSN/ISBN: 0015-5640 PMID: 1107191 Document Number: 85232
In dogs, with the aid of the modified transplantation method in which the prevertebral ganglia (splanchnic and aorticorenal) are transferred along with the kidney, the intrarenal adrenergic nerves of the grafted kidneys were preserved. These nerves continue to take part in the regulation of NA concentration at receptor-effector level by releasing and taking up of exogenous NA and thus prevent, to some extent, the full development of denervation supersensitivity throughout the whole period after grafting and the denervation contraction shortly after transplantation especially. The denervation contraction may cause the functional crisis shortly after surgery. The autonomic innervation of the transplanted kidney is probably worth preserving.