Ultrastructure of the prolactin cells of the pituitary gland of female rats after stimulation with norethisterone enanthate

Peter, S.t.; Denereaz, C.; Wagner, R.; Aumuller, G.

Bulletin de l'Association des Anatomistes 59(165): 489-498

1975


ISSN/ISBN: 0376-6160
PMID: 1203559
Document Number: 83007
Prolactin cells from the pituitary gland of female rats were studied under the electron microscope and by the freeze-etch method after treatment with norethisterone enanthate. Prolonged treatment caused a pathological secretory process in this type of cells. They increase greatly both in number and in volume, and particularly the Golgi apparatus proliferates. At the same time, however, exocytosis is reduced, and for this reason the serum prolactin level is also greatly reduced.

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