Amantadine-induced livedo reticularis: a report of two cases
Hayes, B.B.; Cook-Norris, R.H.; Miller, J.L.; Rodriguez, A.; Zic, J.A.
Journal of Drugs in Dermatology Jdd 5(3): 288-289
2006
ISSN/ISBN: 1545-9616 PMID: 16573266 Document Number: 8234
In the last several years, amantadine has been increasingly prescribed for akinesia in Parkinson's disease and to combat fatigue associated with multiple sclerosis. Amantadine is a well-known medication involved in drug-induced livedo reticularis (LR), yet remains under-reported in the English literature. We describe 2 patients with amantadine livedo reticularis: one patient with multiple sclerosis had, previous to this eruption, tolerated 4 years of amantadine therapy without adverse reactions and another patient with Parkinson's disease who developed LR 1 month after starting amantadine.
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