The action of halothane in gausing abortion

Wittmann, R.; Doenicke, A.; Heinrich, H.; Pausch, H.

Der Anaesthesist 23(1): 30-35

1974


ISSN/ISBN: 0003-2417
PMID: 4458468
Document Number: 79782
The abortifacient effects of halothane and nitrous oxide were studie d in 505 adult female rats. Anesthesia with a mixture of nitrous oxide, oxygen, and halothane in the 6th-10th week of pregnancy resulted in spontaneous abortion in 44% of the animals; the incidence was 50.5% in the 7th-9th week. The number of abortions was directly proportional to the amount of halothane administered. Nitrous oxide was followed by abortion in 13%, an incidence within the normal limits for spontaneous a bortion.

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