The influence of the halothane test on heart parameters, OCT-activity, acid-base balance and blood electrolytes in halothane-sensitive pigs and in pigs premedicated with a beta-blocker (propranolol)
Schulman, A.
Acta Veterinaria Scandinavica 23(2): 153-160
1982
ISSN/ISBN: 0044-605X PMID: 7148596 Document Number: 185268
The heart and liver functions, blood electrolytes and acid-base balance were studied in halothane-sensitive and insensitive pigs. An inhibition of the hyperthermia reaction was attempted by an i/v injection of propranolol. The pulse rate of sensitive pigs was shown to be elevated already at the onset of halothane narcosis. No other differences between sensitive and nonsensitive pigs were observed from the electrocardiogram. Ectopic beats and arrythmia appeared only in one halothane-sensitive pig which died soon after the test. The serum OCT activity showed no abnormalities. Hyperkalaemia and acidosis occurred but Ca was not elevated in halothane-sensitive animals. The slight elevation in Na was thought to be caused by haemoconcentration. A propranolol injection delayed but did not inhibit the halothane reaction.