Effect of 5-fluorocytosine on the internal amino-acid pool and protein synthesis in Candida albicans
Polak, A.
Pathologia et Microbiologia 40(3): 132-134
1974
ISSN/ISBN: 0031-2959 PMID: 4602002 Document Number: 76241
No change in the initial uptake of 14C-histidine in 5-fluorocytosine (5-FC)-treated C. albicans was seen, but an actual increase occurred after a longer period of incubation. Most of the histidine taken up by 5-FC-treated cells remained free in the internal pool. Incorporation into proteins was found to be significantly lower in treated than in normal cells.
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