Updates on AIDS cryptosporidiosis: a review
Garrido Dávila, J.I.; Ramírez Ronda, C.H.
Boletin de la Asociacion Medica de Puerto Rico 83(2): 65-68
1991
ISSN/ISBN: 0004-4849 PMID: 1675056 Document Number: 700032
The transmission, pathogenesis, dissemination, diagnosis and treatment of Cryptosporidium infections in man are reviewed, with particular reference to immunosuppression. Cryptosporidium is responsible for only 2-5% of acute enteric conditions. Mortality in immunosuppressed and AIDS patients due to diarrhoea is nearly 80%. No effective treatment is available currently; most forms of therapy (spiramycin, erythromycin and somatostatin) result in only a reduction in the amount of daily stool volume. The most promising is Zidovudine, which seems to reduce both the stool volume and to clear oocysts from the body.
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