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Hypolipidemic and antioxidant activities of volatile oils from fresh leaves of Michelia martini Levl

Ling-Hua, L.; Jing, H.; Hai-Yan, L.; Yan-Hua, C.; Xiao-Ying, Y.; Zhi-Ping, G.

Pakistan Journal of Pharmaceutical Sciences 32(1(Special): 383-389

2019

ISSN/ISBN: 1011-601X
PMID: 30852474
Document Number: 698409
.This study aimed to investigate the hypolipidemic and antioxidant activities of volatile oils from Michelia martini Levl. The antioxidant property of volatile oils from Michelia martini in vitro was investigated by establishment of various systems. High fat diet induced rats were used to assess the hypolipidemic and antioxidant activities of Michelia martini volatile oils in vivo. The level of total cholesterol, triglycerides, high density lipoprotein cholesterol, low density lipoprotein cholesterol, alanine transaminase, aspartate aminotransferase, alkaline phosphatase and gamma-glutamyl transpeptidase in serum, and the activities of catalase, malondialdehyde, super oxide dismutase and glutathione in liver of rats were assayed by standard procedures. Our results showed that Michelia martini exhibits strong hypolipidemic and antioxidant activities both in vitro and vivo. Our data were also supplemented with histopathological studies on liver tissues and aorta sections of rats.

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