Mitomycin C HIVEC. Update and results in high risk patients
Guerrero-Ramos, Félix.; Castellano-Gauna, D.; García-Rojo, E.; Duarte-Ojeda, Jé.Manuel.; de la Rosa-Kehrmann, F.; Villacampa-Aubá, F.
Archivos Espanoles de Urologia 71(4): 417-425
2018
ISSN/ISBN: 0004-0614 PMID: 29745931 Document Number: 696780
Adjuvant endovesical treatment is a research field in constant exploration with the aim to minimize the risk of recurrence and progression of non muscle invasive bladder tumors. Over the last years, the administration of chemotherapy in a chemo hyperthermia regimen has been added to the existing regimens. There are various systems for its administration, but this article focus on HIVEC (Hyperthermic IntraVEsical Chemotherapy) and its current status. In this review article we update the results of this system in the case-scenarios it has been used (preoperative with ablative intention and as adjuvant therapy with prophylactic purposes), tolerance and security issues, on-going clinical trials and future perspectives.