Progress of long non-coding RNA in regulating cell autophagy in cancer
Liu, W.W.; Shen, X.J.; Ju, S.Q.
Zhonghua Zhong Liu Za Zhi 40(5): 321-324
2018
ISSN/ISBN: 0253-3766 PMID: 29860756 Document Number: 695458
肿瘤的发生是一个多因素参与的复杂过程,通常与癌基因的激活或抑癌基因的失活有关。长链非编码RNA(lncRNA)在肿瘤的形成过程中发挥了重要的生物学作用,而自噬作为细胞内的一种代谢过程,也在肿瘤细胞分化、转移及耐药等方面扮演了重要角色,成为近年来的研究热点。深入研究和了解lncRNA与自噬的关系以及具体作用机制,有助于揭示肿瘤发生、发展,为肿瘤的诊断和治疗提供新的思路。.
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