Calculating osmotic pressure of glucose solutions according to ASOG model and measuring it with air humidity osmometry

Wei, G.; Zhan, T.; Zhan, X.; Yu, L.; Wang, X.; Tan, X.; Li, C.

Pakistan Journal of Pharmaceutical Sciences 29(5): 1657

2016


ISSN/ISBN: 1011-601X
PMID: 27731826
Document Number: 690548
The osmotic pressure of glucose solution at a wide concentration range was calculated using ASOG model and experimentally determined by our newly reported air humidity osmometry. The measurements from air humidity osmometry were compared with the well-established freezing point osmometry and ASOG model calculations at low concentrations and with only ASOG model calculations at high concentrations where no standard experimental method could serve as a reference for comparison. Results indicate that air humidity osmometry measurements are comparable to ASOG model calculations at a wide concentration range, while at low concentrations freezing point osmometry measurements provide better comparability with ASOG model calculations.

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