Endometriosis and Glanzmanns thrombasthenia
Imperiale, L.; Manganaro, L.; Ticino, A.; Piacenti, I.; Anastasi, E.; Resta, S.; Benedetti Panici, P.; Porpora, M.G.
Journal of Biological Regulators and Homeostatic Agents 30(3): 877-882
2016
ISSN/ISBN: 0393-974X PMID: 27655515 Document Number: 690166
Glanzmanns thrombasthenia (GT) is a rare bleeding syndrome characterized by deficiency or defect of platelet aggregation complex. The pathogenesis of endometriosis is controversial but the strongest evidence leans towards retrograde menstruation. GT probably predisposes to endometriosis. The management of women affected by this disease can be difficult due to the risk of bleeding complications, especially during surgical treatment. We describe the cases of three sisters affected by endometriosis and GT, referred to our Department, who received different therapeutic management.