Diagnostics and Correction of Thrombohemorrhagic Disorders in Patients with Giant Uterine Myoma at the Perioperative Stage of Treatment
Tarabrin, O.A.; Tyutrin, I.I.; Gavrichenkov, D.G.; Shcherbakov, S.S.; Mazurenko, A.I.; Turenko, A.V.
Anesteziologiia i Reanimatologiia 61(6): 450-453
2016
ISSN/ISBN: 0201-7563 PMID: 29894615 Document Number: 689361
The aim of the study was to reduce perioperative blood loss in patients with giant uterine myoma. As a result of studies have provided evidence that the use of anti fibrinolytic therapy as intravenous infusion of tranexamic acid for 30 minutes before the surgery in a dose of 20 mg/kg followed by infusion of 5 mg/kg per hour for the first postoperative day, helped to reduce perioperative blood loss by 29%. Hemoglobin level was higher by 10% (p < 0,05), blood loss was lower by 29% (p < 0,05), the length of stay in hospital was reduced by 24% (p < 0,05) in patients of the second group on the second postoperative day.