Diagnostics and correction of thrombohemorrhagic impairments in patients with purulent-septic complications in obstetrics and gynecology
Kolesnichenko, A.P.; Gritsan, G.V.; Gritsan, A.I.; Skorobogatov, A.Iu.
Anesteziologiia i Reanimatologiia 2004(4): 41-44
2004
ISSN/ISBN: 0201-7563 PMID: 15468555 Document Number: 580538
The clinical course of thrombohemorrhagic complications was studied in 56 patients, aged 18 to 38, with sepsis, which developed due to obstetric and gynecologic processes on days 1, 3, 5, 7 and 10 after surgery. The patients were treated, 1999-2003, at the obstetric intensive-care and consultation center, MUZA Maternity Hospital No. 1, Krasnoyarsk. The coagulation, anti-coagulation and fibrinolytic chains of the coagulation cascade and vascular-thrombotic hemostasis were dynamically evaluated. Thrombohemorrhagic complications in severe sepsis and septic shock manifested themselves as hypercoagulation stage in 52% of observations. The hemostasis correction does not only require the elimination of changes in the hemocoagulation system but also the intensive care of the present systemic dysfunctions.