Reparative Activity of Original Substance Based on Alginic Acid
Zelentsov, R.N.; Krylov, I.A.; Nezgovorov, D.V.; Martynova, N.A.; Shamshur, Y.I.
Eksperimental'naia i Klinicheskaia Farmakologiia 79(1): 38-44
2016
ISSN/ISBN: 0869-2092 PMID: 27159957 Document Number: 687312
The influence of an original substance based on enzymatically destructed alginic acid on the reparative activity has been studied using an experimental model of planar aseptic wound. Toxicity of the test compound was evaluated and its effective dose was determined using curiozin as the reference drug. It is found that the test compounds is non-toxic. It is established that the pharmacological activity of the reference drug (curiozin) is lower on the average by 3.5% (δ = 0.021) than that of the original pharmaceutical substance based on destructed alginic acid