Recurrent adult onset Henoch-Schonlein Purpura: a case report
Gaskill, N.; Guido, B.; Magro, C.
Dermatology Online Journal 22(8)
2016
ISSN/ISBN: 1087-2108 PMID: 27617937 Document Number: 685879
Henoch-Schonlein purpura is an immunoglobulin A (IgA)-immune complex mediated leukocytoclastic vasculitis that classically manifests with palpable purpura, abdominal pain, arthritis, and hematuria or proteinuria. The condition is much more predominant in children (90% of cases) and commonly follows an upper respiratory infection. We present a case of recurrent Henoch-Schonlein purpura (HSP) complicated by nephritis in an adult female initially categorized as IgA nephropathy (IgAN). We review the pathophysiologic basis of HSP nephritis as the variant of HSP accompanied by renal involvement and its pathogenetic commonality with IgA nephropathy.