Studies on chemical constituents of Zhuang medicine Excoecaria venenata and their cytotoxic activity

Ning, D.-s.; Yan, X.-x.; Huang, S.-s.; Cheng, L.; Li, J.; Pan, Z.-h.

Zhongguo Zhong Yao Za Zhi 40(4): 686-690

2015


ISSN/ISBN: 1001-5302
PMID: 26137691
Document Number: 685186
Fourteen compounds were isolated from 95% ethanol extract by silica gel, MCI, and ODS column chromatography. These compounds were respectively identified as quercetin (1), kaempferol (2), (+)-catechin (3), fraxin (4), protocatechuic acid (5), gallic acid (6), methyl gallate (7), ethyl gallate (8), apocynol A (9), baccatin (10), cerevisterol (11), ellagic acid (12), 3, 3',4'-tri-0-methylellagic acid(13) and N-benzoyl-L-phenylalaninyl-N-benzoyl-L-phenylalaninate(14) by analyzing their spectral data and comparing with the previously reported literatures. Except for gallic acid (6), all other compounds were isolated from this plant for the first time. Compounds 1, 2 and 6 showed moderate anti-proliferation activities on tumor cells.

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