Validation of the Russian Version of the Questionnaire to Assess the Effectiveness of Surgical Treatment of Patients with Anterior Urethral Stricture (Patient-Reported Outcome Measure for Urethral Stricture Surgery (Prom-Uss) : a Pilot Study
Bazaev, V.V.; Shibaev, A.N.; Pavlova, Y.V.
Urologiia 2015(5): 15-9; Quiz 20-1
2015
ISSN/ISBN: 1728-2985 PMID: 26859931 Document Number: 681985
Currently, the patient-reported outcome measures are widely used for the analysis of the effectiveness of treatment. In 2011, the questionnaire to assess the effectiveness of treatment of men with anterior urethral stricture (PROM-USS) was proposed. Study objective: during validation to perform pilot testing of the Russian version of the PROM-USS questionnaire for determining its psychometric properties (reliability, validity and sensitivity). The study involved 35 men with anterior urethral stricture, who completed PROM-USS questionnaires before and 6 months after surgery. The questionnaire consists of 14 questions and 2 visual analogue scales (VAS), combined in 2 domains: 1--evaluation of lower urinary tract symptoms (LUTS), 2--assessment of the quality of life; questionnaire also includes questions about treatment satisfaction. The reliability, validity and sensitivity of the PROM-USS questionnaire were assessed. High intraclass correlation (ICC) coefficients (0.7-0.96) and Cronbach's α = 0.76, indicated reliability of the questionnaire. The correlation coefficient between LUTS scoring and an index of maximum urine flow rate (Qmax)--R = -0.81 (p < 0.05) confirmed the criterion validity. After the surgery, the total LUTS scoring decreased from 14.0 ± 0.72 to 5.66 ± 0.58 (P < 0.05); VAS EQ-5D index increased from 51.43 ± 5.3 to 71.42 ± 7.64 (P = 0.01) with an increase of Qmax from 3.4 ± 0.3 to 17.9 ± 0.9 ml/s (P < 0.001), indicating the sensitivity of questionnaire to changes. Ninety-four percent of men were satisfied and very satisfied with the result of the surgery; 88% had residual LUTS not affecting the quality of life or affecting slightly. For the final conclusions about the feasibility of this tool, further studies involving a larger number of patients are required.